Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, is associated with arrhythmogenic disorders and is a risk factor for sudden cardiac death. Two genome-wide association studies (GWAS) of variation in the QT interval in population-based cohorts now report association with variants in a subset of ion channel genes and other new associations.
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Shah, S., Pitt, G. Genetics of cardiac repolarization. Nat Genet 41, 388–389 (2009). https://doi.org/10.1038/ng0409-388
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DOI: https://doi.org/10.1038/ng0409-388
