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The resequencing imperative

The possibility of deep population resequencing of genes has generated excitement over its potentially promising role in understanding complex human traits. A new study has now demonstrated the utility of this approach, reporting the resequencing of a lipid metabolism gene in a large multiethnic population and definitively showing that coding variants in the gene are associated with plasma triglyceride levels.

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Topol, E., Frazer, K. The resequencing imperative. Nat Genet 39, 439–440 (2007). https://doi.org/10.1038/ng0407-439

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  • DOI: https://doi.org/10.1038/ng0407-439

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