During meiosis, crossovers are regulated such that each pair of chromosomes has at least one crossover and multiple crossovers are evenly spaced. A new study leads to surprising insights regarding the timing of crossover regulation through the analysis of two genes involved in synaptonemal complex elongation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Sturtevant, A.H.Z. Induct. Abstammungs-Vererbungsl 13, 234–287 (1915).
Bishop, D.K. & Zickler, D. Cell 117, 9–15 (2004).
Shinohara, M., Oh, S., Hunter, N. & Shinohara, A. Nat. Genet. 40, 299–309 (2008).
Malavasic, M.J. & Elder, R.T. Mol. Cell. Biol. 10, 2809–2819 (1990).
Sym, M., Engebrecht, J.A. & Roeder, G.S. Cell 72, 365–378 (1993).
Lynn, A., Soucek, R. & Borner, G.V. Chromosome Res. 15, 591–605 (2007).
Zickler, D. & Kleckner, N. Annu. Rev. Genet. 33, 603–754 (1999).
King, J.S. & Mortimer, R.K. Genetics 126, 1127–1138 (1990).
Mehrotra, S. & McKim, K.S. PLoS Genet. 2, e200 (2006).
Carpenter, A.T. Cell 77, 957–962 (1994).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Berchowitz, L., Copenhaver, G. Division of labor among meiotic genes. Nat Genet 40, 266–267 (2008). https://doi.org/10.1038/ng0308-266
Issue Date:
DOI: https://doi.org/10.1038/ng0308-266