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QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2

Nature Geneticsvolume 21pages158160 (1999) | Download Citation

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References

  1. 1

    Encinas, J.A. et al. J. Immunol. 157, 2186– 2192 (1996).

  2. 2

    Sundvall, M. et al. Nature Genet. 10, 313– 317 (1995).

  3. 3

    Todd, J.A. et al. Nature 351, 542–547 (1991).

  4. 4

    Ghosh, S. et al. Nature Genet. 4, 404– 409 (1993).

  5. 5

    Vyse, T.J. & Todd, J.A. Cell 85, 311 –318 (1996).

  6. 6

    Podolin, P.L. et al. Mamm. Genome 9, 283– 286 (1998).

  7. 7

    Denny, P. et al. Diabetes 46, 695–700 (1997).

  8. 8

    Bernard, C.C. et al. J. Mol. Med. 75, 77– 88 (1997).

  9. 9

    Chesnut, K., She, J.X., Cheng, I., Muralidharan, K. & Wakeland, E.K. Mamm. Genome 4, 549– 554 (1993).

  10. 10

    Teuscher, C., Wardell, B.B., Lunceford, J.K., Michael, S.D. & Tung, K.S. J. Exp. Med. 183, 631–637 (1996).

  11. 11

    Matesanz, F., Alcina, A. & Pellicer, A. Immunogenetics 38, 300– 303 (1993).

  12. 12

    Classen, J.B. & Shevach, E.M. Autoimmunity 15, 55–59 (1993).

  13. 13

    Lenardo, M.J. et al. Int. Rev. Immunol. 13, 115– 134 (1995).

  14. 14

    Sadlack, B. et al. Eur. J. Immunol. 25, 3053– 3059 (1995).

  15. 15

    Zamvil, S. et al. Nature 317, 355–358 (1985).

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Acknowledgements

We thank A. Abbas and L. Nicholson for review of the manuscript. These studies were carried out with the support of grants from the National Institutes of Health (RO1 NS 30843, RO1 NS 35685 and PO1 AI 39671) and National Multiple Sclerosis Society (RG 2571 and 2320) to V.K.K.

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Author notes

  1. C.E.S. and J.G.S. are supported by Howard Hughes Medical Institute.

Affiliations

  1. Department of Medicine, Center for Neurologic Diseases, Brigham & Women's Hospital, Boston, 02115, Massachusetts , USA

    • Jeffrey A. Encinas
    • , Akiko Mukasa
    • , Howard L. Weiner
    •  & Vijay K. Kuchroo
  2. Department of Autoimmune Diseases Research, Merck Research Laboratories, Rahway, 07065, New Jersey, USA

    • Linda S. Wicker
  3. Department of Cellular and Molecular Pharmacology, Merck Research Laboratories, Rahway, 07065, New Jersey, USA

    • Laurence B. Peterson
  4. Department of Veterinary Pathobiology, The University of Illinois at Urbana–Champaign, Urbana, 61802, Illinois , USA

    • Cory Teuscher
  5. Department of Pathology, Stanford University School of Medicine and Laboratory Service, Veterans Affairs Medical Center, Palo Alto, 94304, California, USA

    • Raymond Sobel
  6. Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, 02115, Massachusetts, USA

    • Christine E. Seidman
    •  & J.G. Seidman

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Correspondence to Vijay K. Kuchroo.

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https://doi.org/10.1038/5941

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