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Dissecting dyskeratosis

Dyskeratosis congenita is a rare but fatal syndrome characterized by bone marrow failure. A new mouse model informs the ongoing debate on its molecular pathogenesis.

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References

  1. Heiss, N.S. et al. Nat. Genet. 19, 32–38 (1998).

    Article  CAS  Google Scholar 

  2. Meier, U.T. & Blobel, G. J. Cell Biol. [correction appeared in 140, 447] 127, 1505–1514 (1994).

    Google Scholar 

  3. Jiang, W., Middleton, K., Yoon, H.-J., Fouquet, C. & Carbon, J. Mol. Cell. Biol. 13, 4884–4893 (1993).

    Article  CAS  Google Scholar 

  4. Lafontaine, D.L.J., Bousquet-Antonelli, C., Henry, Y., Caizergues-Ferrer, M. & Tollervey, D. Genes Dev. 12, 527–537 (1998).

    Article  CAS  Google Scholar 

  5. Mitchell, J.R., Wood, E. & Collins, K. Nature 402, 551–555 (1999).

    Article  CAS  Google Scholar 

  6. Ruggero, D. et al. Science 299, 259–262 (2003).

    Article  CAS  Google Scholar 

  7. Decatur, W.A. & Fournier, M.J. Trends Biochem. Sci. 27, 344–351 (2002).

    Article  CAS  Google Scholar 

  8. Blasco, M.A. et al. Cell 91, 25–34 (1997).

    Article  CAS  Google Scholar 

  9. Vulliamy, T. et al. Nature 413, 432–435 (2001).

    Article  CAS  Google Scholar 

  10. Yu, Y.T., Shu, M.D. & Steitz, J.A. EMBO J. 17, 5783–5795 (1998).

    Article  CAS  Google Scholar 

  11. Jady, B.E. & Kiss, T. EMBO J. 20, 541–551 (2001).

    Article  CAS  Google Scholar 

  12. Fortes, P. et al. Mol. Cell. Biol. 19, 6543–6553 (1999).

    Article  CAS  Google Scholar 

  13. Cadwell, C., Yoon, H.-J., Zebarjadian, Y. & Carbon, J. Mol. Cell. Biol. 17, 6175–6183 (1997).

    Article  CAS  Google Scholar 

  14. Kendall, A. et al. Proc. Natl. Acad. Sci. USA 97, 13108–13113 (2000).

    Article  CAS  Google Scholar 

Download references

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Meier, U. Dissecting dyskeratosis. Nat Genet 33, 116–117 (2003). https://doi.org/10.1038/ng0203-116

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