Several new studies report mutations in the gene GATA2 in three different familial syndromes characterized by predisposition to myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Before the onset of MDS and AML, patients with similar GATA2 mutations had distinct hematological abnormalities.
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Hyde, R., Liu, P. GATA2 mutations lead to MDS and AML. Nat Genet 43, 926–927 (2011). https://doi.org/10.1038/ng.949
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DOI: https://doi.org/10.1038/ng.949
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