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Pediatric cancer genomics, a play rather than a portrait

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Relapsed neuroblastoma is common, frequently lethal and poorly studied and poses a major treatment challenge. Two new studies shed light on the genomic landscape of recurrent neuroblastoma and demonstrate profound differences between the disease at diagnosis and relapse.

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Figure 1: Recurrent neuroblastoma arises from a treatment-resistant clone of the primary tumor.

Marina Corral Spence/Nature Publishing Group

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Correspondence to Michael D Taylor.

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Ramaswamy, V., Taylor, M. Pediatric cancer genomics, a play rather than a portrait. Nat Genet 47, 851–852 (2015). https://doi.org/10.1038/ng.3366

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