The genetic determinants of progression from premalignant Barrett's esophagus to esophageal adenocarcinoma are not known. A new study reports genomic sequence analyses of this progression and uses the insights gained to identify high-risk Barrett's esophagus in a new non-endoscopic test.
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Vaughan, T. From genomics to diagnostics of esophageal adenocarcinoma. Nat Genet 46, 806–807 (2014). https://doi.org/10.1038/ng.3047
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DOI: https://doi.org/10.1038/ng.3047
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