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Altered Neural Protein in Murine Muscular Dystrophy

Abstract

WE have previously presented evidence, obtained from transplantation studies, which suggested that murine (129/ReJ) muscular dystrophy was of neurogenic origin1, and Gallup and Dubowitz2 have confirmed and further delineated these findings with tissue culture techniques involving spinal cord and muscle. Thus it now seems that the fault lies within the spinal cord or peripheral nerve; yet the nature of this gene-determined defect and the manner in which the dystrophy is produced remain unknown.

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References

  1. Salafsky, B., Nature, 229, 270 (1971).

    Article  CAS  Google Scholar 

  2. Gallup, B., and Dubowitz, V., Nature, 243, 287 (1973).

    Article  CAS  Google Scholar 

  3. Bradley, W. G., and Jenkinson, M., J. neurol. Sci., 18, 227 (1973).

    Article  CAS  Google Scholar 

  4. Hosokawa, H., J. comp. Neurol., 11, 407 (1959).

    Article  Google Scholar 

  5. Mandel, P., Functional and Structural Proteins of the Nervous System (Advances in Experimental Medicine and Biology), 32, 241 (Plenum, London, 1972).

    Book  Google Scholar 

  6. Morell, P., Greenfield, S., Norton, W. T., and Wisniewski, H., ibid., 251.

  7. O'Brien, J. S., Sampson, E. L., and Stern, M. B., J. Neurochem., 14, 357 (1967).

    Article  CAS  Google Scholar 

  8. Mehl, E., and Wolfgram, F., J. Neurochem., 16, 1091 (1969).

    Article  CAS  Google Scholar 

  9. Uyemura, K., Tobari, C., Hirano, S., and Tsukada, U., J. Neurochem., 19, 2607 (1972).

    Article  CAS  Google Scholar 

  10. Polosa, C., Can. J. Physiol. Pharmac., 45, 1033 (1967).

    Article  CAS  Google Scholar 

  11. Al-Amood, W. S., Buller, A. J., and Pope, R., Nature, 244, 225 (1973).

    Article  CAS  Google Scholar 

  12. Fairbanks, G., Stock, T. L., and Wallach, D. F. H., Biochemistry, 10, 2606 (1971).

    Article  CAS  Google Scholar 

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SALAFSKY, B., STIRLING, C. Altered Neural Protein in Murine Muscular Dystrophy. Nature New Biology 246, 126–128 (1973). https://doi.org/10.1038/newbio246126a0

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