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Asynchronous Changes in Circulating LH and FSH after the Gonadotrophin Releasing Hormone

Nature New Biology volume 246, pages 22–23 (1973)Cite this article

Abstract

Hypothalamic extracts have been reported to contain two gonadotrophin releasing factors, one for luteinising hormone (LH) and one for follicle stimulating hormone (FSH)1,2 but only a single peptide has been isolated from these preparations3. This hypothalamic hormone has been shown to be a decapeptide which is capable of releasing both LH and FSH in humans4. We report here the relationship between the changes in circulating concentrations of both LH and FSH during continuous infusion of this material.

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Authors and Affiliations

  1. Medical Professorial Unit, and Department of Chemical Pathology, St Bartholomew's Hospital, London, EC1A 7BE

    C. H. MORTIMER, G. M. BESSER, D. J. GOLDIE, JANET HOOK & A. S. McNEILLY

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  1. C. H. MORTIMER
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  2. G. M. BESSER
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  3. D. J. GOLDIE
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  4. JANET HOOK
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  5. A. S. McNEILLY
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MORTIMER, C., BESSER, G., GOLDIE, D. et al. Asynchronous Changes in Circulating LH and FSH after the Gonadotrophin Releasing Hormone. Nature New Biology 246, 22–23 (1973). https://doi.org/10.1038/newbio246022a0

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