Abstract
THREE years after bicuculline was first reported to be a specific antagonist1 to γ-aminobutyric acid (GABA), its value as such still is not settled definitely2–7. Nevertheless, many workers now claim the demonstration of GABA-mediated synapses in various parts of vertebrate and invertebrate nervous systems on the basis of suppression by bicuculline of GABA-induced inhibition of firing rates of neurones.
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SWAGEL, M., IKEDA, K. & ROBERTS, E. Effects of GABA and Bicuculline on Conductance of Crayfish Abdominal Stretch Receptor. Nature New Biology 244, 180–181 (1973). https://doi.org/10.1038/newbio244180a0
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DOI: https://doi.org/10.1038/newbio244180a0
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