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Induction of Lymphoma in Owl Monkeys with Heated, Non-cytopathogenic Herpesvirus saimiri

Nature New Biology volume 242, pages 28–30 (1973)Cite this article

Abstract

THE inoculation of Herpesvirus saimiri (HVS) heated to 56° C for 30 min into several marmosets (Sanguinus sp.) and an owl monkey (Aotus trivirgatus) has previously been described. No illness was reported following the inoculation1. In our laboratories, two owl monkeys were inoculated with heated HVS shown to be non-cytopathogenic in owl monkey kidney (OMK) and Vero cells. Both monkeys developed malignant lymphoma with lymphogenous leukaemia in a manner identical to animals inoculated with untreated HVS2.

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References

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Authors and Affiliations

  1. National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20014

    D. V. ABLASHI, W. F. LOEB, G. PEARSON, MARION G. VALERIO, G. R. ARMSTRONG, H. RABIN, ELIZABETH W. KINGSBURY & URSULA HEINE

  2. Litton Bionetics, Inc, Kensington, Maryland, 20795

    D. V. ABLASHI, W. F. LOEB, G. PEARSON, MARION G. VALERIO, G. R. ARMSTRONG, H. RABIN, ELIZABETH W. KINGSBURY & URSULA HEINE

Authors
  1. D. V. ABLASHI
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  2. W. F. LOEB
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  3. G. PEARSON
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  4. MARION G. VALERIO
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  5. G. R. ARMSTRONG
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  6. H. RABIN
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  7. ELIZABETH W. KINGSBURY
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  8. URSULA HEINE
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ABLASHI, D., LOEB, W., PEARSON, G. et al. Induction of Lymphoma in Owl Monkeys with Heated, Non-cytopathogenic Herpesvirus saimiri. Nature New Biology 242, 28–30 (1973). https://doi.org/10.1038/newbio242028a0

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  • DOI: https://doi.org/10.1038/newbio242028a0

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