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Relationship between Catecholamines and ACTH: Effects of 6-Hydroxy-dopamine

Abstract

THE precise nature of the relationship, if any, between brain catecholamines (CA) and ACTH secretion has been actively debated. The most popular hypothesis is that of Van Loon et al.1–4, who have proposed that CA exert an inhibitory control over ACTH secretion. Others have failed to demonstrate any direct correlation between CA levels and ACTH secretion4,5, while yet another group has demonstrated a facilitatory effect6,7.

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LIPPA, A., ANTELMAN, S., FAHRINGER, E. et al. Relationship between Catecholamines and ACTH: Effects of 6-Hydroxy-dopamine. Nature New Biology 241, 24–25 (1973). https://doi.org/10.1038/newbio241024a0

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