Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letters to Editor
  • Published:

HL-A and Kidney Transplantation

Nature New Biology volume 238, pages 150–152 (1972)Cite this article

Abstract

AT present the role of HL-A antigens in the rejection of organ transplants is uncertain; we therefore wish to report the results of renal transplantations, under known HL-A compatibility conditions, performed in France since 1959. The 179 cases already published2 have now increased to 416 cases3 including 84 sibling (SS), parent-to-child (PC) and 253 unrelated (UR) allografts. Only three cases were excluded from the analysis, which was similar to that previously used2. We calculated the probability of incompatibility for the non-determined HL-A antigens, assuming the presence of four HL-A antigens of similar strength in each individual. Differences between antigens having serological similarities (cross-reactions) were considered in a first analysis as incompatibilities and in a second analysis as identities.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Amos, D. B., and Yunis, E. J., Transplantation, 2, 6 (1971).

    Google Scholar 

  2. Hors, J., Feingold, N., Fradelizi, D., and Dausset, J., Lancet, i, 609 (1971).

  3. Dausset, J., and Hors, J., Presse Médicale, 1, 1273 (1972).

    CAS  Google Scholar 

  4. Rychlichova, M., Demant, P., and Ivanyi, P., Folia Biol. (Praha), 16, 218 (1970).

    Google Scholar 

  5. Gatti, R. A., Meuwissen, H. J., Terasaki, P. I., and Good, R. A., Tissue Antigens, 1, 239 (1971).

    Article  CAS  Google Scholar 

  6. Dupont, B., Nielsen, L. S., and Svejgaard, S., Lancet, ii, 1336 (1971).

  7. Lebrun, A., Sasportes, M., Lebrun, D., and Dausset, J., CR. Acad. Sci. Paris, 273, 22, 2130 (1971).

    Google Scholar 

  8. Klein, J., Folia Biol. (Praha), 12, 168 (1966).

    CAS  Google Scholar 

  9. Demant, P., and Nouza, K., Folia Biol. (Praha), 17, 6, 410 (1971).

    Google Scholar 

  10. Demant, P., Folia Biol. (Praha), 16, 273 (1970).

    CAS  Google Scholar 

  11. Dausset, J., Rapaport, F., Legrand, L., Colombani, J., and Marcelli-Barge, A., in Histocompatibility Testing 1970, 381 (Munksgaard, Copenhagen, 1970).

    Google Scholar 

  12. Koch, C. T., Frederike, E., Eysvoogel, V. P., and Van Rood, J. J., Lancet, ii, 1334 (1971).

  13. Sengar, D. P. S., Mickey, M. R., Myhre, B. A., Chen, H. H., and Terasaki, P. I., Transfusion, 11, 251 (1971).

    Article  CAS  Google Scholar 

  14. Ivanyi, P., and Dausset, J., Vox Sang., 11, 326 (1966).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut de Recherches sur les Maladies du Sang, Hôpital Saint Louis, 75, Paris, X

    J. DAUSSET & J. HORS

Authors
  1. J. DAUSSET
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. HORS
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

DAUSSET, J., HORS, J. HL-A and Kidney Transplantation. Nature New Biology 238, 150–152 (1972). https://doi.org/10.1038/newbio238150a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/newbio238150a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing