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Inhibition of Reproduction in Trypanosoma lewisi by Ouabain

Nature New Biology volume 237, pages 253–255 (1972)Cite this article

Abstract

Trypanosoma lewisi usually produces a benign parasitaemia in rats. The parasites multiply only during the first few days after infection. Reproducing populations contain organisms that vary greatly in shape, size and total length. The coefficient of variation (CV) of the total length of the parasites measures this variability and is a sensitive index of reproductive activity1. The CV is high, about 25%, early in the infection when reproduction is intense, and thereafter decreases during infection until the trypanosomes become nearly uniform in size at about the tenth day of infection after which mostly non-reproducing forms are found2.

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Author notes

  1. CURTIS L. PATTON

    Present address: Department of Microbiology, Yale University School of Medicine, New Haven, Connecticut, 06510

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  1. Rockefeller University, New York, New York, 10021

    CURTIS L. PATTON

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  1. CURTIS L. PATTON
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PATTON, C. Inhibition of Reproduction in Trypanosoma lewisi by Ouabain. Nature New Biology 237, 253–255 (1972). https://doi.org/10.1038/newbio237253a0

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