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Axonal Transport in Nigro-striatal Neurones

Abstract

AXONAL transport of macromolecules has received considerable attention in recent years1–3 and has been studied particularly in peripheral nerve, in the optic tract4–7 and in the hypothalamico-hypophysial tract8–10. We now report evidence for axonal transport in discrete groups of neurones with cell bodies and projections which lie entirely within the brain, that is the nigro-striatal tract.

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References

  1. Barondes, S. H., Neurosci. Res. Symp. Summ., 3, 191 (1969).

    Google Scholar 

  2. Dahlstrom, A., Phil. Trans. Roy. Soc., 261, 325 (1971).

    Article  CAS  Google Scholar 

  3. Grafstein, B., Adv. Biochem. Psychopharmacol., 1, 11 (1969).

    CAS  PubMed  Google Scholar 

  4. Grafstein, B., Science, 157, 196 (1967).

    Article  CAS  Google Scholar 

  5. Grafstein, B., Science, 172, 177 (1971).

    Article  CAS  Google Scholar 

  6. Elam, J. S., and Agranoff, B. W., J. Neurochem., 18, 375 (1971).

    Article  CAS  Google Scholar 

  7. Karlsson, J. O., and Sjostrand, J., J. Neurochem., 18, 749 (1971).

    Article  CAS  Google Scholar 

  8. Norstrom, A., Brain Res., 28, 131 (1971).

    Article  CAS  Google Scholar 

  9. Norstrom, A., and Sjostrand, J., J. Neurochem., 18, 2007 (1971).

    Article  CAS  Google Scholar 

  10. Norstrom, A., and Sjostrand, J., J. Neurochem., 18, 2017 (1971).

    Article  CAS  Google Scholar 

  11. Cole, M., Nauta, W. J. H., and Mehler, W. R., Trans. Amer. Neurol. Assoc., 89, 74 (1964).

    CAS  Google Scholar 

  12. Carpenter, M. B., and Strominger, N. L., Amer. J. Anat., 121, 41 (1967).

    Article  CAS  Google Scholar 

  13. Anden, N. E., Dahlstrom, A., Fuxe, K., Larsson, K., Olsen, L., and Ungerstedt, U., Acta Physiol. Scand., 67, 313 (1966).

    Article  CAS  Google Scholar 

  14. Moore, R. Y., Bhatnagar, R. K., and Heller, A., Brain Res., 30, 119 (1971).

    Article  CAS  Google Scholar 

  15. Noble, E. P., Wurtman, R. J., and Axelrod, J., Life Sci., 6, 281 (1967).

    Article  CAS  Google Scholar 

  16. Anden, N. E., Carlsson, A., Dahlstrom, A., Fuxe, K., Hillarp, N. A., and Larsson, K., Life Sci., 3, 523 (1964).

    Article  CAS  Google Scholar 

  17. Poirier, L. J., McGeer, E. G., Larochelle, L., McGeer, P. L., Bedard, P., and Boucher, R., Brain Res., 14, 147 (1967).

    Article  Google Scholar 

  18. Breese, G. R., and Traylor, T. O., J. Pharm. Exp. Ther., 174, 413 (1970).

    CAS  Google Scholar 

  19. Breese, G. R., and Traylor, T. D., Brit. J. Pharmacol., 42, 88 (1971).

    Article  CAS  Google Scholar 

  20. Fibiger, H. C., Lonsbury, B., Cooper, H. P., and Lytle, L. D., Nature, 236, 209 (1972).

    CAS  Google Scholar 

  21. McGeer, E. G., Gibson, S., and McGeer, P. L., Canad. J. Biochem., 45, 1557 (1967).

    Article  CAS  Google Scholar 

Download references

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FIBIGER, H., PUDRITZ, R., McGEER, P. et al. Axonal Transport in Nigro-striatal Neurones. Nature New Biology 237, 177–179 (1972). https://doi.org/10.1038/newbio237177a0

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  • DOI: https://doi.org/10.1038/newbio237177a0

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