Abstract
SPECIALIZED tissues which synthesize only a small number of different proteins offer obvious advantages as sources of specific and pure messenger RNAs (mRNAs). Presumptive mRNAs have been isolated and partially characterized from reticulocytes1,2, muscle3, myelomas4 and eye lens5. The messenger role of 9S RNA from reticulocytes has been established by its ability to direct the synthesis of haemoglobin in cell-free systems from reticulocytes2 and Krebs 11 ascites tumour cells6, and in Xenopus oocytes7. We show here that 10S and 14S RNA fractions from calf lens direct the synthesis of different polypeptide components of lens crystallin in the ascites cell-free system. These results complement and extend the demonstration, in the accompanying article8, that 14S lens RNA is translated in the reticulocyte lysate.
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MATHEWS, M., OSBORN, M., BERNS, A. et al. Translation of Two Messenger RNAs from Lens in a Cell Free System from Krebs II Ascites Cells. Nature New Biology 236, 5–7 (1972). https://doi.org/10.1038/newbio236005a0
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DOI: https://doi.org/10.1038/newbio236005a0
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