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Induction of Group-specific Interspecies Antibody in a Cat by Immunization with Disrupted Feline Leukaemia Virus

Nature New Biology volume 235, pages 14–15 (1972)Cite this article

Abstract

“ALL mice, cats and virtually all chickens seem to be completely refractory to developing antibody to the group-specific, gs, antigens characteristic of the RNA tumour viruses of their own species.”1 This is explained on the basis of an immune tolerance induced in early embryonic life by the expression of these antigens before the development of immune competence. Avian group-specific (gs) antibody has been demonstrated in the sera of immunized chickens by the immunodiffusion (Ouchterlony)2 and complement fixation inhibition3 tests. This report is to record the production of gs antibody in a cat which had been immunized with gs antigen from disrupted feline leukaemia virus (FeLV).

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Authors and Affiliations

  1. Department of Pathology, New York State Veterinary College, Cornell University, Ithaca, New York, 14850

    F. DE NORONHA, J. E. POST, N. L. NORCROSS & C. G. RICKARD

Authors
  1. F. DE NORONHA
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  2. J. E. POST
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  3. N. L. NORCROSS
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  4. C. G. RICKARD
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DE NORONHA, F., POST, J., NORCROSS, N. et al. Induction of Group-specific Interspecies Antibody in a Cat by Immunization with Disrupted Feline Leukaemia Virus. Nature New Biology 235, 14–15 (1972). https://doi.org/10.1038/newbio235014a0

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