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Surface-bound Immunoglobulin as a Marker of B Lymphocytes in Man

Abstract

IMMUNOLOGICAL reactions in many species depend on two functionally different types of small lymphocytes, thymus-derived T lymphocytes and bone marrow-derived B lymphocytes1. In the mouse, the θ antigen is a marker for T lymphocytes, while membrane-bound Ig is found on θ-negative lymphocytes2. This has raised the question whether the presence of surface-bound Ig3 may be regarded as a marker for B lymphocytes. We have obtained data indicating that this is the case with human lymphocytes.

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FRÖLAND, S., NATVIG, J. & BERDAL, P. Surface-bound Immunoglobulin as a Marker of B Lymphocytes in Man. Nature New Biology 234, 251–252 (1971). https://doi.org/10.1038/newbio234251a0

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