Abstract
AS it is not widely appreciated that diffusion within complex media can be strikingly and often qualitatively different from that in simple liquids such as water, there is confusion concerning transport processes across biological membranes1,2. We would like to draw attention to some fundamental differences between the diffusion process in simple liquids and that in more complex media-non-porous networks of hydrophobic polymers and biological membranes.
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References
Lieb, W. R., and Stein, W. D., Nature, 224, 240 (1969).
Lieb, W. R., and Stein, W. D., in Current Topics in Membranes and Transport (edit. by Bronner, F., and Kleinzeller, A.), 2 (Academic Press, New York, in the press).
Hitchcock, D. I., in Physical Chemistry of Cells and Tissues (edit. by Höber, R.) (Churchill, London, 1947).
Stein, W. D., The Movement of Molecules across Cell Membranes (Academic Press, New York, 1967).
Kunins, C. A., and Kwei, T. K., in Diffusion in Polymers (edit. by Crank, J., and Park, G. S.) (Academic Press, London, 1968).
Fujita, H., in Diffusion in Polymers (edit. by Crank, J., and Park, G. S.) (Academic Press, London, 1968).
Tanford, C., Physical Chemistry of Macromolecules (Wiley, New York, 1961).
Soll, A. H., J. Gen. Physiol., 50, 2565 (1967).
Meares, P., Polymers: Structure and Bulk Properties (Van Nostrand, London, 1965).
Aitken, A., and Barrer, R. M., Trans. Faraday Soc., 51, 116 (1955).
Prager, S., and Long, F. A., J. Amer. Chem. Soc., 73, 4072 (1951).
Wang, J. H., Robinson, C. V., and Edelman, I. S., J. Amer. Chem. Soc., 75, 466 (1953).
Longsworth, L. G., J. Phys. Chem., 58, 770 (1954).
Dorsey, N. E., in International Critical Tables (edit. by Washburn E. W.), 5 (McGraw-Hill, New York, 1929).
Kokes, R. J., and Long, F. A., J. Amer. Chem. Soc., 75, 6142 (1953).
Long, F. A., and Thompson, L. J., J. Polymer Sci., 14, 321 (1954).
Doty, P., J. Chem. Phys., 14, 244 (1946).
Diamond, J. M., and Wright, E. M., Ann. Rev. Physiol., 31, 581 (1969).
Collander, R., Physiol. Plant., 7, 420 (1954).
Collander, R., Physiol. Plant., 12, 139 (1959).
Oura, E., Suomalainen, H., and Collander, R., Physiol. Plant., 12, 534 (1959).
Jacobs, M. H., Glassman, H. N., and Parpart, A. K., J. Cell. Comp. Physiol., 7, 197 (1935).
Wartiovaara, V., in Handbuch der Pflanzenphysiologie (edit. by Ruhland, W.), 2 (Springer, Berlin, 1956).
Bunch, W., and Edwards, C., J. Physiol., 202, 683 (1969).
Hantzsch, A., and Vagt, A., Z. Phys. Chem., 38, 705 (1901).
Johnson, S. M., and Bangham, A. D., Biochim. Biophys. Acta, 193, 92 (1969).
Davson, H., A Textbook of General Physiology, third ed. (Churchill, London, 1964).
Jacobs, M. H., and Parpart, A. K., Biol. Bull, 73, 380 (1937).
Bärlund, H., Protoplasma, 30, 70 (1938).
Macy, R., J. Ind. Hyg. Toxicol., 30, 140 (1948).
Rogers, C. E., Stanett, V., and Szwarc, M., in Permeability of Plastic Films and Coated Papers to Gases and Vapors (edit. by Kouris, M.) (Tech. Assoc. Pulp and Paper Ind., New York, 1962).
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LIEB, W., STEIN, W. Implications of Two Different Types of Diffusion for Biological Membranes. Nature New Biology 234, 220–222 (1971). https://doi.org/10.1038/newbio234220a0
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DOI: https://doi.org/10.1038/newbio234220a0
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