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Haemoglobin Miyada, a β—δ Fusion Peptide (Anti-Lepore) Type discovered in a Japanese Family

Nature New Biology volume 234, pages 218–220 (1971)Cite this article

Abstract

SEVERAL slow-moving abnormal haemoglobins associated with thalassaemia-like stigmata have been encountered during the past 13 yr1–6. The non-α-chains of these haemoglobins are the fusion products7 of δ and β-chains; the N-terminal end containing a part of the β-chain joined to a fragment of the β -chain ending in the C-terminal. But no structural variants of anti-Lepore type (fused in reverse β-δ) have yet been demonstrated. In a systematic screening survey for abnormal haemoglobins8, we discovered a new variant named Hb Miyada which may possess a fused non-α-chain.

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Authors and Affiliations

  1. First Department of Medicine, Kyushu University, 1276, Katakasu, Fukuoka

    YOSHIRO OHTA, KOTARO YAMAOKA, IKUO SUMIDA & TOSHIYUKI YANASE

Authors
  1. YOSHIRO OHTA
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  2. KOTARO YAMAOKA
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  3. IKUO SUMIDA
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  4. TOSHIYUKI YANASE
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OHTA, Y., YAMAOKA, K., SUMIDA, I. et al. Haemoglobin Miyada, a β—δ Fusion Peptide (Anti-Lepore) Type discovered in a Japanese Family. Nature New Biology 234, 218–220 (1971). https://doi.org/10.1038/newbio234218a0

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