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Specificity of Debranching Enzymes

An Erratum to this article was published on 05 January 1972

Abstract

THE debranching enzymes are a most important group because, with the amylases and phosphorylases, they completely degrade starch and glycogen to the monosaccharide level. Some of the earlier preparations of debranching enzymes were not homogeneous and their use led to erroneous conclusions about their specificity. These views were later qualified by studies using more highly purified preparations. For example, some preparations of yeast isoamylase hydrolysed α-1,6-D-glucosidic linkages in both glycogen and oligosaccharide α-dextrins1, but the latter activity is now no longer ascribed to isoamylase2.

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References

  1. Manners, D. J., and Khin Maung, Chem. and Ind., 950 (1955).

  2. Gunja, Z. H., Manners, D. J., and Khin Maung, Biochem. J., 81, 392 (1961).

    Article  CAS  Google Scholar 

  3. Manners, D. J., Ann. Rep. Chem. Soc., 62, 590 (1966).

    Google Scholar 

  4. Enzyme Nomenclature. Recommendations (1964) of the Intern. Union Biochemistry.

  5. Hobson, P. N., Whelan, W. J., and Peat, S., Biochem. J., 47, xxxix (1950); J. Chem. Soc., 1451 (1971).

    Article  CAS  Google Scholar 

  6. MacWilliam, I. A., and Harris, G., Arch. Biochem. Biophys., 84, 442 (1966).

    Article  Google Scholar 

  7. Maruo, B., and Kobayashi, T., Nature, 167, 606 (1951).

    Article  CAS  Google Scholar 

  8. Manners, D. J., and Rowe, K. L., Carbohydrate Res., 9, 107 (1969).

    Article  CAS  Google Scholar 

  9. Harada, T., Yokobayashi, K., and Misaki, A., Appl. Microbiol., 16, 1439 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Abdullah, M., Catley, B. J., Lee, E. Y. C., Robyt, J., Wallenfels, K., and Whelan, W. J., Cereal Chem., 43, 111 (1966).

    CAS  Google Scholar 

  11. Walker, G. J., Bioehem. J., 108, 33 (1968).

    CAS  Google Scholar 

  12. Manners, D. J., Marshall, J. J., and Yellowlees, D., Biochem. J., 116, 539 (1970).

    Article  CAS  Google Scholar 

  13. Underkofler, L. A., and Roy, D. K., Cereal Chem., 28, 18 (1951).

    CAS  Google Scholar 

  14. Denault, L. J., and Underkofler, L. A., Cereal Chem., 40, 618 (1963).

    CAS  Google Scholar 

  15. Larner, J., and McNickle, C. M., J. Biol. Chem., 215, 723 (1955).

    CAS  PubMed  Google Scholar 

  16. Smith, E. E., Taylor, P. M., and Whelan, W. J., Carbohydrate Metabolism and its Disorders, 1, 89 (Academic Press, New York, 1969).

    Google Scholar 

  17. Lee, E. Y. C., Carter, J. H., Nielsen, L. D., and Fischer, E. H., Biochemistry, 9, 2347 (1970).

    Article  CAS  Google Scholar 

  18. Ueda, S., and Nanri, N., Appl. Microbiol., 15, 492 (1967).

    CAS  PubMed  PubMed Central  Google Scholar 

  19. Seiji, M., J. Biochem., 40, 519 (1953).

    Article  CAS  Google Scholar 

  20. Kobayashi, T., J. Jap. Soc. Starch Sci., 17, 61 (1969).

    CAS  Google Scholar 

  21. Peat, S., Whelan, W. J., Hobson, P. N., and Thomas, G. J., J. Chem. Soc., 4440 (1954).

  22. Manners, D. J., and Sparra, K. L., J. Inst. Brew., 72, 360 (1966).

    Article  CAS  Google Scholar 

  23. Drummond, G. S., Smith, E. E., and Whelan, W. J., FEBS Lett., 9, 136 (1970).

    Article  CAS  Google Scholar 

  24. Yokobayashi, K., Misaki, A., and Harada, T., Biochem. Biophys. Acta, 212, 458 (1970).

    CAS  PubMed  Google Scholar 

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MANNERS, D. Specificity of Debranching Enzymes. Nature New Biology 234, 150–151 (1971). https://doi.org/10.1038/newbio234150a0

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