Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letters to Editor
  • Published:

Sequence Studies on Precursor 16S Ribosomal RNA of Escherichia coli

Abstract

THE 16S and 23S rRNAs of E. coli are known to be synthesized through intermediates of marginally. higher S values (about 17S and 24S). Although various authors1–3 have reported the presence of these precursors, no sequence studies have been presented. Nevertheless, there is strong but indirect evidence3 that the precursor 16S rRNA (p16) is about 200 residues longer than 16S rRNA (ml6). In contrast, the evidence suggests that the precursor 23S rRNA has few or no further residues.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Hecht, N. B., and Woese, C. R., J. Bact., 95, 986 (1968).

    CAS  PubMed  Google Scholar 

  2. Adesnik, M., and Levinthal, C., J. Mol. Biol., 46, 281 (1969).

    Article  CAS  Google Scholar 

  3. Dahlberg, A. E., and Peacock, A. C., J. Mol. Biol., (in the press).

  4. Sanger, F., Brownlee, G. G., and Barrell, B. G., J. Mol. Biol., 13, 373 (1965).

    Article  CAS  Google Scholar 

  5. Brownlee, G. G., Sanger, F., and Barrell, B. G., J. Mol. Biol., 34, 379 (1968).

    Article  CAS  Google Scholar 

  6. Brownlee, G. G., and Sanger, F., Europ. J. Biochem., 11, 395 (1969).

    Article  CAS  Google Scholar 

  7. Fellner, P., Ehresmann, C., and Ebel, J. P., Nature, 225, 26 (1970).

    Article  CAS  Google Scholar 

  8. Jordan, B., J. Bact., 101, 657 (1970).

    CAS  PubMed  Google Scholar 

  9. Dahlberg, A. E., Dingman, C. W., and Peacock, A. C., J. Mol. Biol., 41, 139 (1969).

    Article  CAS  Google Scholar 

  10. Peacock, A. C., and Dingman, C. W., Biochemistry, 6, 1818 (1967).

    Article  CAS  Google Scholar 

  11. Adams, J. M., Jeppesen, P. G. N., Sanger, F., and Barrell, B. G., Nature, 223, 1009 (1969).

    Article  CAS  Google Scholar 

  12. Brownlee, G. G., and Sanger, F., J. Mol. Biol., 23, 337 (1967).

    Article  CAS  Google Scholar 

  13. Dahlberg, J., Nature, 232, 52 (1971).

    Article  Google Scholar 

  14. Brownlee, G. G., Nature (in the press, 1971).

  15. Forget, B. G., and Jordan, B., Science, 167, 382 (1970).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BROWNLEE, G., CARTWRIGHT, E. Sequence Studies on Precursor 16S Ribosomal RNA of Escherichia coli. Nature New Biology 232, 50–52 (1971). https://doi.org/10.1038/newbio232050a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/newbio232050a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing