Abstract
THE reduction of methaemoglobin is one of the few oxidation-reduction reactions known to occur in the mature red blood cell. Approximately 3% of the circulating haemoglobin of an adult man is oxidized each day to methaemoglobin1 and so a methaemoglobin reduction system is needed in the cell to maintain a low concentration of methaemoglobin (normally less than 1% of the total haemoglobin2).
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Distribution of valence electrons of the flavin cofactor in NADH-cytochrome b5 reductase
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HULTQUIST, D., PASSON, P. Catalysis of Methaemoglobin Reduction by Erythrocyte Cytochrome b5 and Cytochrome b5 Reductase. Nature New Biology 229, 252–254 (1971). https://doi.org/10.1038/newbio229252a0
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DOI: https://doi.org/10.1038/newbio229252a0
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