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Risk stratification in acute decompensated heart failure: the role of cardiac troponin

Nature Clinical Practice Cardiovascular Medicine volume 5, pages 680–681 (2008)Cite this article

Abstract

Cardiac troponins provide important prognostic information in patients with acute decompensated heart failure. In a large study by the ADHERE Investigators, 6.2% of 67,924 patients with acute decompensated heart failure were positive for cardiac troponin; these individuals had lower blood pressure and lower ejection fraction than those who were negative for troponin. The study revealed that in-hospital mortality was significantly higher for troponin-positive patients than for troponin-negative individuals (8.0% vs 2.7%; P<0.001). Future studies need to define which treatment changes could improve outcome in troponin-positive patients with acute decompensated heart failure.

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Author notes

  1. Department of Internal Medicine, University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland chmueller@uhbs.ch

Authors and Affiliations

  1. C Mueller is Professor of Medicine at the University of Basel and Deputy Head of the Division of Internal Medicine at the University Hospital Basel, Basel, Switzerland.,

    Christian Mueller

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  1. Christian Mueller
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The author declares no competing financial interests.

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Mueller, C. Risk stratification in acute decompensated heart failure: the role of cardiac troponin. Nat Rev Cardiol 5, 680–681 (2008). https://doi.org/10.1038/ncpcardio1342

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