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Does coating stents with titanium oxynitride reduce restenosis?

Nature Clinical Practice Cardiovascular Medicine volume 2, pages 436–437 (2005)Cite this article

Windecker S et al. (2005) Randomized comparison of a titanium-nitride-oxide–coated stent with a stainless steel stent for coronary revascularization: the TiNOX trial. Circulation 111: 2617–2622

Restenosis due to neointimal proliferation is a major limitation of percutaneous coronary interventions. Stent surface material can influence restenosis rates, with gold-coated stents leading to an increased risk of restenosis; similarly, stainless steel stents increase the risk of restenosis in patients who are allergic to nickel. The single-blind, randomized, prospective, TiNOX study was performed at centers in Switzerland and Germany, and compared the safety and efficacy of stents coated with titanium oxynitride (TiNOX) with that of uncoated stainless steel stents in patients with de novo, native coronary artery lesions.

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  1. Rebecca Ireland
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Ireland, R. Does coating stents with titanium oxynitride reduce restenosis?. Nat Rev Cardiol 2, 436–437 (2005). https://doi.org/10.1038/ncpcardio0285

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