Quantitative detection of H2O2, which is increasingly recognized as an intracellular messenger, remains a challenge for cell biologists. The development of molecular probes that fluoresce upon H2O2-mediated removal of a boronate-based protecting group, rather than upon nonspecific oxidation, demonstrates that this challenge is not insurmountable.
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Rhee, S. Measuring H2O2 produced in response to cell surface receptor activation. Nat Chem Biol 3, 244–246 (2007). https://doi.org/10.1038/nchembio0507-244
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DOI: https://doi.org/10.1038/nchembio0507-244
