News & Views | Published:

Ion channels get flashy

Nature Chemical Biology volume 2, pages 1113 (2006) | Download Citation

Subjects

Ion channels have essential roles in the nervous system. An engineered ligand-gated channel with a photoactivated switch will be useful for addressing several issues in neuronal signaling.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    et al. Nat. Chem. Biol. 2, 47–52 (2006).

  2. 2.

    , & Nat. Chem. Biol. 1, 360–365 (2005).

  3. 3.

    , , , & Nat. Neurosci. 7, 1381–1386 (2004).

  4. 4.

    & in Dynamic Studies in Biology: Phototriggers, Photoswitches and Caged Biomolecules (eds. Goeldner, M. & Givens, R.) (Wiley-VCH Verlag, Weinheim, Germany, 2005).

  5. 5.

    , , & Chem. Biol. 2, 391–400 (1995).

  6. 6.

    , , & Science 309, 755–758 (2005).

  7. 7.

    et al. J. Gen. Physiol. 75, 207–232 (1980).

  8. 8.

    et al. Science 304, 743–746 (2004).

  9. 9.

    , , , & Neuron 20, 619–624 (1998).

  10. 10.

    , , , & Nat. Biotechnol. 21, 1505–1508 (2003).

  11. 11.

    , & Curr. Opin. Chem. Biol. 9, 576–584 (2005).

Download references

Author information

Affiliations

  1. Hagan Bayley is in the Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK. hagan.bayley@chem.ox.ac.uk

    • Hagan Bayley

Authors

  1. Search for Hagan Bayley in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nchembio0106-11

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing