Owing to population aging, the number of individuals suffering from Alzheimer's disease is rapidly increasing; consequently, finding an effective treatment is becoming an increasingly important goal. The use of O-GlcNAcase inhibitors is emerging as a promising track to prevent and slow disease progression.
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Lefebvre, T. Recall sugars, forget Alzheimer's. Nat Chem Biol 8, 325–326 (2012). https://doi.org/10.1038/nchembio.920
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DOI: https://doi.org/10.1038/nchembio.920
