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Nuclear replication

Hidden iron-sulfur clusters

Nature Chemical Biology volume 8, pages 24–25 (2012)Cite this article

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The multisubunit DNA polymerases of eukaryotes have iron-sulfur centers that are crucial for polymerase assembly and therefore the integrity of the nuclear genome.

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Figure 1: Role of mitochondria and Fe-S clusters in nuclear DNA replication.

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  1. Scott Bailey is in the Department of Biochemistry and Molecular Biology, Johns Hopkins University School of Public Health, Baltimore, Maryland, USA.,

    Scott Bailey

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  1. Scott Bailey
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Correspondence to Scott Bailey.

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The author declares no competing financial interests.

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Bailey, S. Hidden iron-sulfur clusters. Nat Chem Biol 8, 24–25 (2012). https://doi.org/10.1038/nchembio.737

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