Cell membrane–bound G protein–coupled receptors are traditionally thought to stimulate cell proliferation by addressing the nuclear replication machinery, but we now learn that they also activate cytosolic nucleotide factories, the purinosomes.
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Katie Vicari
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A dynamic mass redistribution device has been provided to E.K. by Corning Inc.
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Mohr, K., Kostenis, E. Purinosomes under GPCR control. Nat Chem Biol 7, 860–861 (2011). https://doi.org/10.1038/nchembio.716
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DOI: https://doi.org/10.1038/nchembio.716
