Designed expansion of hydrophobic contacts converts a coiled-coil tetramer to a true hexamer, a new protein fold previously deemed unlikely to exist. The complex has a central channel sized to allow passage of water molecules.
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Kennan, A. Charting a new course in coiled coils. Nat Chem Biol 7, 859–860 (2011). https://doi.org/10.1038/nchembio.714
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DOI: https://doi.org/10.1038/nchembio.714
