Stem cell therapeutics hold great promise, but obtaining optimal cell populations for transplantation remains a major challenge. High-throughput screens of zebrafish embryonic cells have enabled identification of small molecules that can direct the fate of pluripotent stem cells toward tissue-specific progenitors with high therapeutic potential.
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Rando, T. Of fish and men. Nat Chem Biol 10, 91–92 (2014). https://doi.org/10.1038/nchembio.1449
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DOI: https://doi.org/10.1038/nchembio.1449