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Not just passing through

Identifying the genes responsible for each step of a natural product biosynthesis has allowed the synthesis to be 'hijacked' to make bioactive compounds, and reveals that some suspected transporter enzymes could have other important roles in fungal defence systems.

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Figure 1: The biosynthesis of pyripyropene A and some related bioactive compounds.


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Correspondence to Jon Clardy.

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Crawford, J., Clardy, J. Not just passing through. Nature Chem 2, 805–807 (2010).

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