The first synthesis of the all-cis isomer of 1,2,3,4,5,6-hexafluorocyclohexane, a molecule with one hydrocarbon face and one fluorocarbon face, is a tour de force of organofluorine chemistry and opens up new possibilities for molecular design.
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Santschi, N., Gilmour, R. A Janus cyclohexane ring. Nature Chem 7, 467–468 (2015). https://doi.org/10.1038/nchem.2240
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DOI: https://doi.org/10.1038/nchem.2240
