Discovering and validating new targets is urgently required to tackle the rise in resistance to antimalarial drugs. Now, inhibition of the enzyme N-myristoyltransferase has been shown to prevent the formation of a critical subcellular organelle in the parasite that causes malaria, leading to death of the parasite.
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Krysiak, J., Sieber, S. Knockout for malaria. Nature Chem 6, 93–94 (2014). https://doi.org/10.1038/nchem.1854
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DOI: https://doi.org/10.1038/nchem.1854
