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Processive catalysis

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Nature Chemistry volume 5, pages 899–900 (2013)Cite this article

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Processive catalysis is frequent in nature, but much less common in synthetic systems. Now, a semisynthetic biohybrid catalytic system is reported that oxidizes DNA in a processive manner.

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Figure 1: The catalytic assembly is formed from the trimeric ring-shaped clamp protein gp45 (represented in red) attached to three copies of a synthetic manganese tetramethyl pyridinium porphyrin complex (green).

DNA © JEZPER/ALAMY

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Authors and Affiliations

  1. Leonard Prins and Paolo Scrimin are in the Department of Chemical Sciences, University of University of Padova, Via Marzolo 1, 35131 Padova, Italy,

    Leonard J. Prins & Paolo Scrimin

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  1. Leonard J. Prins
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  2. Paolo Scrimin
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Correspondence to Leonard J. Prins or Paolo Scrimin.

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Prins, L., Scrimin, P. Thread and cut. Nature Chem 5, 899–900 (2013). https://doi.org/10.1038/nchem.1785

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