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DNA structure

Visualizing the quadruplex

The direct observation and quantification of G-quadruplex structures formed from DNA in human cells during the cell cycle demonstrate the biological importance of these structures and point towards opportunities for targeting them with small-molecule drugs.

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Correspondence to Adam Siddiqui-Jain or Laurence H. Hurley.

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Siddiqui-Jain, A., Hurley, L. Visualizing the quadruplex. Nature Chem 5, 153–155 (2013).

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