A simple aldehyde has been shown to catalyse an intermolecular hydroamination, not by activating either reaction partner, but simply by bringing them into close proximity.
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References
Laidler, K. J. & King, M. C. J. Phys. Chem. 87, 2657–2664 (1983).
Page, M. I. & Jencks, W. P. Proc. Natl Acad. Sci. USA 68, 1678–1683 (1971).
Tan, K. L. ACS Catalysis 1, 877–886 (2011).
MacDonald, M. J., Schipper, D. J., Ng, P. J., Moran, J. & Beauchemin, A. M. J. Am. Chem. Soc. 133, 20100–20103 (2011).
Diederich, F. & Stang, P. J. Templated Organic Synthesis (Wiley-VCH, 2000).
Pascal, R., Lasperas, M., Taillades, J. & Commeyras, A. New. J. Chem. 11, 235–244 (1987).
Cooper, N. J. & Knight, D. W. Tetrahedron 60, 243–269 (2004).
Bell, K. E., Coogan, M. P., Gravestock, M. B., Knight, D. W. & Thornton, S. R. 38, 8545–8548 (1997).
Rousseau, G. & Breit, B. Angew. Chem. Int. Ed. 50, 2450–2494 (2011).
Sun, X., Worthy, A. D. & Tan, K. L. Angew. Chem. Int. Ed. 50, 8167–8171 (2011).
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Tan, K. Temporary intramolecularity. Nature Chem 4, 253–254 (2012). https://doi.org/10.1038/nchem.1308
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DOI: https://doi.org/10.1038/nchem.1308
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