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This work was supported by NSERC Discovery grants to SI and SR. We thank Dr Josée Lamoureux for technical assistance. DB is a recipient of a postdoctoral fellowship from Fonds de Recherché du Québec-Santé (FRQS). CR-CHUS is an FRQS-funded research center.
DB, JY, SR and SI designed the experiments, analyzed and interpreted data, and wrote the manuscript. DB, EB and XLC performed the experiments. RK and MM assisted in performing the experiments. HK and FB participated in data analysis and in writing the manuscript.
The authors declare no conflict of interest.
Supplementary Information accompanies this paper on the Leukemia website .
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Bobbala, D., Kandhi, R., Chen, X. et al. Interleukin-15 deficiency promotes the development of T-cell acute lymphoblastic leukemia in non-obese diabetes mice with severe combined immunodeficiency. Leukemia 30, 1749–1752 (2016). https://doi.org/10.1038/leu.2016.28