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Burnout in the neonatal intensive care unit and its relation to healthcare-associated infections

Abstract

Objective:

To examine burnout prevalence among California neonatal intensive care units (NICUs) and to test the relation between burnout and healthcare-associated infection (HAI) rates in very low birth weight (VLBW) neonates.

Study Design:

Retrospective observational study of provider perceptions of burnout from 2073 nurse practitioners, physicians, registered nurses and respiratory therapists, using a validated four-item questionnaire based on the Maslach Burnout Inventory. The relation between burnout and HAI rates among VLBW (<1500 g) neonates from each NICU was evaluated using multi-level logistic regression analysis with patient-level factors as fixed effects.

Results:

We found variable prevalence of burnout across the NICUs surveyed (mean 25.2±10.1%). Healthcare-associated infection rates were 8.3±5.1% during the study period. Highest burnout prevalence was found among nurses, nurse practitioners and respiratory therapists (non-physicians, 28±11% vs 17±19% physicians), day shift workers (30±3% vs 25±4% night shift) and workers with 5 or more years of service (29±2% vs 16±6% in fewer than 3 years group). Overall burnout rates showed no correlation with risk-adjusted rates of HAIs (r=−0.133). Item-level analysis showed positive association between HAIs and perceptions of working too hard (odds ratio 1.15, 95% confidence interval 1.04–1.28). Sensitivity analysis of high-volume NICUs suggested a moderate correlation between burnout prevalence and HAIs (r=0.34).

Conclusion:

Burnout is most prevalent among non-physicians, daytime workers and experienced workers. Perceptions of working too hard associate with increased HAIs in this cohort of VLBW infants, but overall burnout prevalence is not predictive.

Introduction

In 1999, the Institute of Medicine estimated that medical errors are responsible for up to 98 000 deaths annually in the United States of America.1 Recent studies suggest that this may have been an underestimate, with the true number of premature deaths related to preventable harm estimated up to 440 000, or approximately one-sixth of the deaths in the country each year.2, 3 Critically ill patients often require fast-paced, complex and precise care, resulting in an increased propensity toward errors along with increased vulnerability. Very low birth weight (VLBW) infants are particularly vulnerable to errors, and adverse events occur with up to 10-fold variation among neonatal intensive care units (NICUs).4

Neonatal infections are especially hazardous, with sequelae including prolonged length of stay,5 adverse neurodevelopmental outcomes6 and increased mortality.5, 7, 8 Higher infection rates have been linked to poor performance in other areas of safety culture including teamwork and safety climate,9, 10 raising concern for burnout as a source of decreased quality of healthcare,11, 12 particularly in relation to critically ill pediatric patients.

Burnout describes a condition of fatigue, detachment and cynicism resulting from prolonged high levels of stress.13 In the critical care setting, burnout rates may be driven by high workload, frequent changes in technology and guidelines, endeavors for high-quality care and emotional challenges of dealing with critically ill patients and their families.14, 15, 16, 17 Burnout affects 27–86% of healthcare workers,18, 19, 20 with over half of physicians reporting burnout21 and around one-third of nurses and physicians meeting criteria for severe burnout.18, 22

Levels of burnout among different types of NICU providers are poorly characterized, and the effect of burnout on neonatal quality of care is unknown. The objectives of this study were to:

  1. 1)

    Describe variation of NICU caregiver burnout by provider characteristics.

  2. 2)

    Analyze the relation between caregiver burnout and healthcare-associated infection (HAI) rates among VLBW (<1500 gm) infants.

Materials and methods

This cross-sectional study links survey data to subsequent clinical outcomes data derived from a population-based clinical registry among 44 California NICUs.

Sample and procedure

Selection of NICUs

The California Perinatal Quality Care Collaborative (CPQCC) is a multi-stakeholder group of public and private neonatal healthcare providers, including over 130 member hospitals and accounting for the majority of preterm infants requiring critical care in the state of California. This cross-sectional survey was performed among a voluntary sample of CPQCC NICUs participating in a Delivery Room Management Quality Improvement Collaborative.23 For the current study, we offered to analyze and provide feedback on a survey of safety culture and workforce engagement to all 61 NICUs who participated in the improvement initiative, 44 of which accepted. The survey was administered at the beginning of the improvement initiative, between June and September 2011.

Staff members with a 0.5 full-time equivalent or greater time commitment to the NICU for at least the four consecutive weeks before survey administration were eligible for inclusion. Paper-based surveys were administered during routine departmental and staff meetings. Respondents returned surveys to a locked box or sealable envelope to maintain confidentiality. Individuals not present in routine meetings were hand-delivered a survey, pencil and return envelope. This administration technique has generated high response rates24, 25 comparable to other studies of similar methodology.26 CPQCC staff administered the survey and transmitted a de-identified data set to Drs. Profit and Tawfik for analysis. Sensitivity analysis was performed using the subset of NICUs with a >50% response rate.

Selection of patients

To capture outcomes subsequent to survey responses, clinical data routinely submitted to the CPQCC by Collaborative members reflecting VLBW infants born between 1 January 2012 and 31 December 2013 were linked to the survey data using unique identifiers for NICUs and patients. Similar to a previous approach used by our group to assess the quality of care delivery in the NICU setting,27, 28, 29 we excluded infants with severe congenital anomalies to reduce systematic bias in infection rates between NICUs that are the result of the need for prolonged parenteral nutrition and surgical intervention. We used multiyear analysis due to the small number of VLBW infants cared for in some institutions. Sensitivity analysis was performed using the subset of NICUs with 5 or more predicted HAIs during the study period, corresponding to NICUs with 60 or more VLBW infants.

Measures

Survey data

Measures relevant for this study were part of a larger survey on safety culture and organizational determinants of quality. The four-question emotional exhaustion subset of the Maslach Burnout Inventory30 was used, which has shown to be reliable and valid in other settings.31 The psychometric properties of the emotional exhaustion subset have performed favorably in recent analysis and suggested its appropriateness as a marker of overall burnout climate.13

A burnout score for each respondent was computed by taking the mean of the four items and transforming it to a 0–100 point scale using the following formula:

Burnout score for a respondent=((mean of the burnout items)−1) × 25

To calculate the percent of respondents who are burned out (that is, percent that agree with burnout items), one calculates the percent of respondents who received a scale score of 50 or higher. This 50% threshold groups ‘neutral’ responses together with ‘agree’ responses as previously described in the literature.13, 25 This metric has been found to be meaningful to providers when used in safety culture assessments.13, 32

We assessed provider perception of nurse staffing adequacy by responses to the following questions from the Safety Attitudes Questionnaire:25 ‘I have the support I need from others in this NICU to care for patients’ and ‘The staffing levels in this NICU are sufficient to handle the number of patients’.

The survey also captured respondent characteristics including job position, years in specialty, primary work area (pediatric, adult or both), gender and predominant work shift. Job positions included attending physicians, fellow physicians, neonatal nurse practitioners, registered nurse, respiratory care practitioners and others.

Clinical data

CPQCC clinical data are equivalent in their definitions to those of the Vermont Oxford Network,33 and undergo a series of quality checks to ensure completeness and accuracy. Healthcare-associated infection rates for each NICU were calculated using standard CPQCC definitions of this measure (also called ‘any nosocomial infection’), which includes any bacterial or fungal infection acquired after 3 days of age. For infants that were transferred to another facility, attribution of infection was defined to include those acquired ‘here’ and ‘here and elsewhere’. We adjusted infection rates according to a severity of illness model we developed in a previous study.29 The variables included gender, gestational age at birth, 5 min Apgar score, small for gestational age (<10th percentile) and birth at the NICU under investigation or outborn.

Data analyses

Descriptive statistics including frequencies, means and s.d.’s were used to describe survey responses and respondent demographics. Burnout prevalence was calculated as described above, resulting in a proportion of total respondents per NICU reporting symptoms of burnout, powered to detect a 10% difference in burnout. For job position analyses, we pooled respondents into ‘physician’ (attending and fellow) and ‘non-physician’ (nurse practitioner, registered nurse, respiratory therapist and other) groups due to the small number of respondents from some of the categories.13, 32

Basic descriptive statistics examined the variation in HAI rates across NICUs, and were correlated to burnout prevalence using Pearson’s correlation coefficients. Hierarchical modeling was employed to account for infant-level clinical risk factors as well as respondent characteristics nested within NICUs.29

All statistical analyses were performed using SAS version 9.4. The study was approved by the Institutional Review Board at Stanford University with waiver of informed consent.

Results

Objective 1 – describe the variation of NICU caregiver burnout by provider type.

Forty-four NICUs participated in this study, with 2073 of 3294 surveys returned for a 62.9% response rate. Individual NICU response rates averaged 69.7% (s.d. 19.8%, range 21.7–100%). Table 1 lists respondent characteristics, which indicated 59.9% of respondents with 11 or more years in their specialty, and 2.4% of respondents with <1 year of experience. Day shift was the most common (47.9%), with night shift (32.2%) and variable shift (15.7%) accounting for the majority of the others.

Table 1 Description of survey respondents and clinical sample. Sensitivity analysis describes NICUs with >60 VLBW infants and >50% survey response rate

One quarter (25.2%±10.1) of respondents reported symptoms consistent with burnout, and individual NICU burnout prevalence ranged from 7.5 to 54.4%. Across NICUs, non-physicians reported higher rates of burnout than physicians (28±11% vs 17±19%, P<0.001), as shown in Figure 1. Respondents with 5 or more years of experience reported higher burnout prevalence than those with fewer than 3 years (29±2% vs 16±6%, P=0.002) as shown in Figure 2.

Figure 1
figure1

Burnout distribution in 44 NICUs, n=2073. Burnout was variable among NICUs (F=2.86, P<0.001) and physicians reported lower burnout prevalence than non-physicians (17±19% vs 28±11%, P<0.001). Physicians in textured bars.

Figure 2
figure2

Burnout by years of service. n=2073 respondents in 44 NICUs, with 95% CIs. Providers with fewer than 3 years experience reported the lowest burnout (16±6% vs 30±4% in >20 years group, P=0.001). *denotes statistical significance (P<0.05) from the fewer than 3 years group.

Objective 2 – analyze the relation between caregiver burnout and HAI rates.

Table 1 shows the characteristics of the clinical sample. Individual NICUs cared for 16 to 399 infants during the study period. Of the 4386 VLBW infants included in the study, 366 (8.3%) experienced an infection during the study period. Seventy-four percent of the infants were cared for at their birth hospital. The risk-adjusted mean percentage of HAI was 8.1% with a range of 0–25.4%. Overall burnout prevalence did not show correlations with HAI rates among the complete cohort of NICUs (r=−0.133, P=0.40).

Table 2 shows patient level associations of burnout items and the burnout scale after adjustment for clinical characteristics. All parameter estimates except feelings of frustration pointed in the expected direction of lower HAI rates with fewer burnout symptoms. Items 1 through 3 and the composite burnout score were not independently associated with HAI rates, although item 1 (‘I feel fatigued when I get up in the morning and have to face another day on the job’; P=0.09) showed a trend towards significance. Item 4 (‘I feel I am working too hard on my job’; P=0.01) was significantly and independently associated with increased HAI rates, such that the odds of an infant contracting a HAI was 11.5% lower with each 10% decrease in NICU respondents reporting this burnout symptom. In the safety culture literature, a 10% change has been regarded as a significant improvement.34

Table 2 Relation between HAI rates and burnout items

Perception of staffing adequacy was negatively associated with burnout prevalence, with results consistent among those reporting sufficient support from others to take care of patients (r=−0.51, P<0.001) and sufficient staffing levels for the number of patients (r=−0.47, P=0.001).

Due to the potential for spurious results in the calculation of infection rates among small NICUs and burnout prevalence among those with low survey response rates, Figure 3 shows the subset of NICUs with greater than 60 VLBW infants (thus 5 or more predicted infections based on the overall HAI rate of 8.3% in this cohort) during the study period and a >50% survey response rate. This subset demonstrated positive but not statistically significant correlation between burnout prevalence and HAI (r=0.34, P=0.14). Patient level associations within this subset are shown in Table 2, which showed significant and independent associations between HAI rates and fatigue (P=0.008) as well as perceptions of working too hard (P=0.002). Additional sensitivity analysis expanded to include patients with severe congenital anomalies found no significant difference as compared with the index cohort.

Figure 3
figure3

Relation between burnout prevalence and adjusted HAI rates, limited to NICUs with 60 or more VLBW infants and >50% survey response rate. n=1188 respondents in 20 NICUs. Positive Pearson’s correlation between burnout and infections was noted, but this was not statistically significant (r=0.34, P=0.14).

Discussion

The major finding of this study is that neonatal provider burnout prevalence is highest among non-physicians, day shift workers and more experienced workers. In addition, perceptions of working too hard are associated with increased HAIs.

Non-physicians reported higher burnout scores on average, a cohort composed primarily of nurses in this study. This is consistent with the lower perceptions of other safety culture components observed among nurses, including safety climate, teamwork and perceptions of management.24, 32 These differences may be due to personal characteristics, job-related factors or a combination of the two. Although fellow physicians reported the lowest burnout prevalence of any cohort, the small number of respondents in this category prevents firm conclusions regarding this subset. Their responses are consistent, however, with the observed trend of lower burnout among less experienced providers in general.

Providers with 5 or more years of experience reported higher rates of burnout than their less experienced peers. It is possible that these providers progressed to burnout as the result of the cumulative effect of repeated stressors. In addition, attrition of burned out providers may counterbalance continued progression of active providers toward burnout, resulting in the observed overall stable prevalence throughout the cohorts of experienced workers.

Providers working primarily day shift also reported higher rates of burnout. Although those with more experience are also more likely to work day shifts, this association was observed independently among workers with 3 or more years of experience. Although night shift work can be challenging in its disruption of circadian rhythm and difficulty coordinating responsibilities outside of work, it is possible that day shift work is more demanding for many due to diagnostics, treatment activities, difficult conversations with families and withdrawals of care being performed during the daytime hours whenever possible.

Overall burnout prevalence did not correlate to HAI rates in the complete cohort of NICUs. However, item-level associations with HAI were seen among those reporting perceptions of working too hard (P=0.01). We speculate that overworked providers may be less likely to follow institutional protocols that they perceive as unnecessary or overly burdensome. They also may be less likely to notice errors or omissions in healthcare delivery. The fear of retaliation or emotional expenditure of voicing concerns to other team members, hospital administration or family members may be insurmountable to a fatigued or overworked provider, instead rationalizing an approach of nonintervention when such errors are identified.35 Conversely, increased HAI rates may contribute to burnout by increasing patient acuity and lengths of stay, exacerbating staffing shortages and contributing to moral distress.8, 36

Nursing staffing shortages have been well-described in the adult literature as potential drivers for nurse burnout and decreased quality of care,37, 38, 39 with nursing shortages also correlated to increased neonatal infections.40 Clinical experience and our findings in this study suggest increased burnout in understaffed units with higher infection rates during times when nurses feel overworked, likely times when attention to detail necessary to prevent infections goes lacking. Therefore, we propose that managers increase sensitivity to episodes of staff shortages, with the use of ‘time outs’ and daily huddles to raise awareness, encourage protocol adherence and peer support, and increase general vigilance.

Over 40% of the NICUs sampled had fewer than 5 predicted HAIs, making accurate assessment of the true HAI rate challenging, and 5 additional NICUs had fewer than 50% of eligible staff respond to the questionnaire, decreasing the ability to accurately determine burnout culture in those units. Sensitivity analysis using the data points least susceptible to these sampling errors showed a moderately strong correlation between burnout and HAI, and all item-level associations with HAI were stronger, most notably among those reporting symptoms of fatigue and perceptions of working too hard. The associations lacking in statistical significance may be limited by small sample size of the subgroup, and the strength of correlation merits further investigation on a larger scale.

This study must be interpreted in the context of its design. This cross-sectional study cannot determine causality of the observed associations, though our findings are in line with prior studies in adults.11, 12 The study is susceptible to response bias at both the NICU and individual respondent levels, as unmotivated NICUs and burned out individuals may have unpredictable propensities to participate. Overall, our response rate of nearly 63% compares favorably with other similar studies.26 Not all respondents worked exclusively in the NICU being evaluated, with likely additional unmeasured predictors and effects of burnout for these individuals. Item-level and subgroup associations resulted from post hoc analyses, and require replication in prospective studies. This study likely carries relevance for the population as a whole despite regional practice variation, as it represents a large neonatal burnout cohort stemming from a diverse sample of NICUs across the most populous state in the United States.

Conclusion

We found prevalent but variable burnout among this cohort of NICUs, with non-physicians and more experienced providers reporting the highest burnout prevalence. Perception of working too hard was associated with increased HAI. NICUs with higher volumes showed a moderate correlation between burnout prevalence and HAI, and HAI rates associated most strongly with symptoms of fatigue and perceptions of working too hard. Interventions to prevent and reduce burnout among NICU providers may be important for reducing HAIs in these fragile patients.

References

  1. 1

    Kohn LT, Corrigan JM, Donaldson MS . To Err is Human: Building a Safer Health System. National Academy Press: Washington, DC, USA, 2000.

    Google Scholar 

  2. 2

    James JT . A new, evidence-based estimate of patient harms associated with hospital care. J Patient Saf 2013; 9 (3): 122–128.

    Article  Google Scholar 

  3. 3

    Makary MA, Daniel M . Medical error-the third leading cause of death in the US. BMJ 2016; 353: i2139.

    Article  Google Scholar 

  4. 4

    Sharek PJ, Horbar JD, Mason W, Bisarya H, Thurm CW, Suresh G et al. Adverse events in the neonatal intensive care unit: development, testing, and findings of an NICU-focused trigger tool to identify harm in North American NICUs. Pediatrics 2006; 118 (4): 1332–1340.

    Article  Google Scholar 

  5. 5

    Stoll BJ, Gordon T, Korones SB, Shankaran S, Tyson JE, Bauer CR et al. Late-onset sepsis in very low birth weight neonates: a report from the National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr 1996; 129 (1): 63–71.

    CAS  Article  Google Scholar 

  6. 6

    Rand KM, Austin NC, Inder TE, Bora S, Woodward LJ . Neonatal infection and later neurodevelopmental risk in the very preterm infant. J Pediatr 2016; 170: 97–104.

    Article  Google Scholar 

  7. 7

    Tsai MH, Hsu JF, Chu SM, Lien R, Huang HR, Chiang MC et al. Incidence, clinical characteristics and risk factors for adverse outcome in neonates with late-onset sepsis. Pediatr Infect Dis J 2014; 33 (1): e7–e13.

    Article  Google Scholar 

  8. 8

    Chapman RL, Faix RG . Persistent bacteremia and outcome in late onset infection among infants in a neonatal intensive care unit. Pediatr Infect Dis J 2003; 22 (1): 17–21.

    Article  Google Scholar 

  9. 9

    Pronovost PJ, Berenholtz SM, Goeschel C, Thom I, Watson SR, Holzmueller CG et al. Improving patient safety in intensive care units in Michigan. J Crit Care 2008; 23 (2): 207–221.

    Article  Google Scholar 

  10. 10

    Weaver SJ, Weeks K, Pham JC, Pronovost PJ . On the CUSP: Stop BSI: evaluating the relationship between central line-associated bloodstream infection rate and patient safety climate profile. Am J Infect Control 2014; 42 (Suppl 10): S203–S208.

    Article  Google Scholar 

  11. 11

    Shanafelt TD, Bradley KA, Wipf JE, Back AL . Burnout and self-reported patient care in an internal medicine residency program. Ann Intern Med 2002; 136 (5): 358–367.

    Article  Google Scholar 

  12. 12

    Shanafelt TD, Balch CM, Bechamps G, Russell T, Dyrbye L, Satele D et al. Burnout and medical errors among American surgeons. Ann Surg 2010; 251 (6): 995–1000.

    Article  Google Scholar 

  13. 13

    Profit J, Sharek PJ, Amspoker AB, Kowalkowski MA, Nisbet CC, Thomas EJ et al. Burnout in the NICU setting and its relation to safety culture. BMJ Qual Saf 2014; 23 (10): 806–813.

    Article  Google Scholar 

  14. 14

    Braithwaite M . Nurse burnout and stress in the NICU. Adv Neonatal Care 2008; 8 (6): 343–347.

    Article  Google Scholar 

  15. 15

    Rochefort CM, Clarke SP . Nurses' work environments, care rationing, job outcomes and quality of care on neonatal units. J Adv Nurs 2010; 66 (10): 2213–2224.

    Article  Google Scholar 

  16. 16

    van Mol MM, Kompanje EJ, Benoit DD, Bakker J, Nijkamp MD . The Prevalence of compassion fatigue and burnout among healthcare professionals in intensive care units: a systematic review. PLoS One 2015; 10 (8): e0136955.

    Article  Google Scholar 

  17. 17

    Portoghese I, Galletta M, Coppola RC, Finco G, Campagna M . Burnout and workload among health care workers: the moderating role of job control. Saf Health Work 2014; 5 (3): 152–157.

    Article  Google Scholar 

  18. 18

    Shanafelt TD, West CP, Sloan JA, Novotny PJ, Poland GA, Menaker R et al. Career fit and burnout among academic faculty. Arch Intern Med 2009; 169 (10): 990–995.

    Article  Google Scholar 

  19. 19

    Mealer M, Burnham EL, Goode CJ, Rothbaum B, Moss M . The prevalence and impact of post traumatic stress disorder and burnout syndrome in nurses. Depress Anxiety 2009; 26 (12): 1118–1126.

    Article  Google Scholar 

  20. 20

    Thomas EJ, Sherwood GD, Mulhollem JL, Sexton JB, Helmreich RL . Working together in the neonatal intensive care unit: provider perspectives. J Perinatol 2004; 24 (9): 552–559.

    Article  Google Scholar 

  21. 21

    Shanafelt TD, Hasan O, Dyrbye LN, Sinsky C, Satele D, Sloan J et al. Changes in burnout and satisfaction with work-life balance in physicians and the general us working population between 2011 and 2014. Mayo Clin Proc 2015; 90: 1600–1613.

    Article  Google Scholar 

  22. 22

    Bellieni CV, Righetti P, Ciampa R, Iacoponi F, Coviello C, Buonocore G . Assessing burnout among neonatologists. J Matern Fetal Neonatal Med 2012; 25 (10): 2130–2134.

    Article  Google Scholar 

  23. 23

    Gould JB . The role of regional collaboratives: the California Perinatal Quality Care Collaborative model. Clin Perinatol 2010; 37 (1): 71–86.

    Article  Google Scholar 

  24. 24

    Profit J, Etchegaray J, Petersen LA, Sexton JB, Hysong SJ, Mei M et al. The Safety Attitudes Questionnaire as a tool for benchmarking safety culture in the NICU. Arch Dis Child Fetal Neonatal Ed 2012; 97 (2): F127–F132.

    Article  Google Scholar 

  25. 25

    Sexton JB, Helmreich RL, Neilands TB, Rowan K, Vella K, Boyden J et al. The safety attitudes questionnaire: psychometric properties, benchmarking data, and emerging research. BMC Health Serv Res 2006; 6: 44.

    Article  Google Scholar 

  26. 26

    Shanafelt TD, Mungo M, Schmitgen J, Storz KA, Reeves D, Hayes SN et al. Longitudinal study evaluating the association between physician burnout and changes in professional work effort. Mayo Clin Proc 2016; 91 (4): 422–431.

    Article  Google Scholar 

  27. 27

    Profit J, Gould JB, Zupancic JA, Stark AR, Wall KM, Kowalkowski MA et al. Formal selection of measures for a composite index of NICU quality of care: Baby-MONITOR. J Perinatol 2011; 31 (11): 702–710.

    CAS  Article  Google Scholar 

  28. 28

    Profit J, Gould JB, Draper D, Zupancic JA, Kowalkowski MA, Woodard L et al. Variations in definitions of mortality have little influence on neonatal intensive care unit performance ratings. J Pediatr 2013; 162 (1): 50–55 e52.

    Article  Google Scholar 

  29. 29

    Profit J, Zupancic JA, Gould JB, Pietz K, Kowalkowski MA, Draper D et al. Correlation of neonatal intensive care unit performance across multiple measures of quality of care. JAMA Pediatr 2013; 167 (1): 47–54.

    Article  Google Scholar 

  30. 30

    Maslach C, Jackson SE . Maslach Burnout Inventory. Consulting Psychologists Press, Inc: Palo Alto, CA, USA, 1981.

    Google Scholar 

  31. 31

    Block M, Ehrenworth JF, Cuce VM, Ng'ang'a N, Weinbach J, Saber S et al. Measuring handoff quality in labor and delivery: development, validation and application of the Coordination of Handoff Effectiveness Questionnaire (CHEQ). Jt Comm J Qual Patient Saf 2013; 39 (5): 213–220.

    Article  Google Scholar 

  32. 32

    Profit J, Etchegaray J, Petersen LA, Sexton JB, Hysong SJ, Mei M et al. Neonatal intensive care unit safety culture varies widely. Arch Dis Child Fetal Neonatal Ed 2012; 97 (2): F120–F126.

    Article  Google Scholar 

  33. 33

    Horbar JD, Soll RF, Edwards WH . The Vermont Oxford Network: a community of practice. Clin Perinatol 2010; 37 (1): 29–47.

    Article  Google Scholar 

  34. 34

    Sexton JB, Berenholtz SM, Goeschel CA, Watson SR, Holzmueller CG, Thompson DA et al. Assessing and improving safety climate in a large cohort of intensive care units. Crit Care Med 2011; 39 (5): 934–939.

    Article  Google Scholar 

  35. 35

    Evans S . Silence kills—challenging unsafe practice. Nurs N Z 2007; 13 (3): 16–19.

    PubMed  Google Scholar 

  36. 36

    Saint S, Veenstra DL, Lipsky BA . The clinical and economic consequences of nosocomial central venous catheter-related infection: are antimicrobial catheters useful? Infect Control Hosp Epidemiol 2000; 21 (6): 375–380.

    CAS  Article  Google Scholar 

  37. 37

    Kunaviktikul W, Wichaikhum O, Nantsupawat A, Nantsupawat R, Chontawan R, Klunklin A et al. Nurses' extended work hours: patient, nurse and organizational outcomes. Int Nurs Rev 2015; 62 (3): 386–393.

    CAS  Article  Google Scholar 

  38. 38

    Jackson M, Chiarello LA, Gaynes RP, Gerberding JL . Nurse staffing and healthcare-associated infections: proceedings from a working group meeting. J Nurs Adm 2002; 32 (6): 314–322.

    Article  Google Scholar 

  39. 39

    Cimiotti JP, Aiken LH, Sloane DM, Wu ES . Nurse staffing, burnout and health care-associated infection. Am J Infect Control 2012; 40 (6): 486–490.

    Article  Google Scholar 

  40. 40

    Cimiotti JP, Haas J, Saiman L, Larson EL . Impact of staffing on bloodstream infections in the neonatal intensive care unit. Arch Pediatr Adolesc Med 2006; 160 (8): 832–836.

    Article  Google Scholar 

Download references

Acknowledgements

We thank the providers from the following NICUs who participated by sharing their assessments: Alta Bates Hospital, Berkeley; Antelope Valley Hospital, Lancaster; Arrowhead Regional Medical Center, Colton; California Pacific Medical Center - California, San Francisco; Cedars Sinai Medical Center, Los Angeles; Children's Hospital Central California, Madera; Children’s Hospital of Orange County, Orange; Community Regional Medical Center - Fresno, Fresno; Doctors Medical Center - Modesto, Modesto; El Camino Hospital-Mountain View, Mountain View; Garfield Medical Center, Monterey Park; Good Samaritan Hospital of Santa Clara Valley–San Jose, San Jose; Harbor UCLA Medical Center, Torrance; Hoag Memorial Presbyterian Hospital, Newport Beach; Hollywood Presbyterian, Los Angeles; Huntington Memorial Hospital, Pasadena; John Muir Medical Center, Walnut Creek; Kaiser-Oakland, Oakland; Kaiser-Walnut Creek, Walnut Creek; Kaweah Delta District Hospital, Visalia; Mercy Medical Center Redding, Redding; Mercy San Juan Hospital, Carmichael; Methodist Hospital of Southern California, Arcadia; Miller Children’s at Long Beach Memorial Medical Center, Long Beach; Orange County Global Medical Center, Santa Ana; Pomona Valley Regional Medical Center, Pomona; Providence Saint Joseph’s Medical Center, Burbank; Providence Tarzana Medical Center, Tarzana; Rady Children’s Hospital at Palomar, Escondido; Redlands Community Hospital, Redlands; Regional Medical Center of San Jose, San Jose; Riverside County Regional Medical Center, Moreno Valley; Salinas Valley Memorial Healthcare System, Salinas; Scripps Memorial Hospital-La Jolla, La Jolla; Sequoia District Hospital, Redwood City; Sharp Chula Vista Medical Center, Chula Vista; Sharp Mary Birch Hospital for Women, San Diego; St. Bernadine Medical Center, San Bernardino; St. Jude Medical Center, Fullerton; Sutter Medical Center-Sacramento, Sacramento; Tri-City Medical Center, Oceanside; UC Davis Medical Center, Sacramento; UC San Francisco Medical Center, San Francisco; Valley Presbyterian Hospital, Van Nuys. This work was supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01 HD084679-01, Co-PI: Sexton and Profit and K24 HD053771-01, PI: Thomas), Texas Children’s Hospital (Pediatrics Pilot Research Fund 33-126, PI: Profit) where Dr. Profit worked at the time of this research, and the Jackson Vaughan Critical Care Research Fund. Special thanks to the Stanford Medicine WellMD Center for their support.

Author contributions

ICMJE criteria for authorship read and met by DT, JBS, PK, PJS, CCN, JR, HCL and JP. DT, JBS, PK, PJS, CCN, JR, HCL and JP agree with the manuscript results and conclusions. JBS and JP designed the experiments/the study. DT, PK, JR and JBS analyzed the data. DT and JP wrote the first draft of the paper. DT, JBS, PK, JR, HCL and JP assisted with approach and selection of data inputs. DT, JBS, PK, PJS, CCN, JR, HCL and JP assisted with interpretation of results. DT, JBS, PK, PJS, JR, HCL and JP contributed to revision of the paper.

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Correspondence to D S Tawfik.

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Tawfik, D., Sexton, J., Kan, P. et al. Burnout in the neonatal intensive care unit and its relation to healthcare-associated infections. J Perinatol 37, 315–320 (2017). https://doi.org/10.1038/jp.2016.211

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