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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Familial recurrence of congenital heart diseases

Journal of Perinatology volume 31, pages 742–743 (2011)Cite this article

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Abstract

Familial recurrence of congenital heart disease (CHD), in particular, d-transposition of great arteries (d-TGA) is rare. However, there have been several reports in the literature of sibling recurrence of total anomalous pulmonary venous return (TAPVR). This is the first case report in the literature, describing mother to offspring recurrence of d-TGA. We describe two cases of non-syndromic CHD with mother to offspring and sibling recurrence. The first case is an antenatally diagnosed d-TGA on fetal echocardiogram at 25 weeks of gestational age in the offspring of a 30-year-old mother with d-TGA. The second case is a sibling reoccurrence of TAPVR diagnosed antenatally at 30 weeks of gestational age, with supradiaphragmatic TAPVR on fetal echocardiogram in a mother, whose first child was diagnosed with infradiaphragmatic TAPVR in infancy.

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Authors and Affiliations

  1. Division of Pediatric Cardiology, University of Minnesota, Minneapolis, MN, USA

    K Thammineni, J Lohr, M Trefz & S Sivanandam

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  1. K Thammineni
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  2. J Lohr
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  3. M Trefz
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  4. S Sivanandam
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Correspondence to S Sivanandam.

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Thammineni, K., Lohr, J., Trefz, M. et al. Familial recurrence of congenital heart diseases. J Perinatol 31, 742–743 (2011). https://doi.org/10.1038/jp.2011.48

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