Abstract
The incidence of measles epidemics has decreased recently owing to the development and widespread use of measles vaccine in the United States of America and Europe. However, repeated measles epidemics have been reported in Japan. Here, the authors report a case of an extremely low body weight infant (ELBWI) whose mother had a measles virus infection. Real-time PCR was performed on the infant's blood and urine samples and skin, nasal secretion, and anal swabs, as well as on the mother's breast milk, blood samples and throat swabs. The infant was found to be positive for measles virus by PCR, but not immunoglobulin M positive. An earlier report showed that there were no such cases in which the patient was found to be positive for measles virus by real-time PCR but was not infected by the measles virus.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Nakata Y, Nakayama T, Ide Y, Kizu R, Koinuma G, Bamba M . Measles virus genome detected up to four months in a case of congenital measles. Acta Paediatri 2002; 91: 1263–1265.
Kugel RB . AMA. J Dis Child 1957; 93 (3): 306–307.
Siegel M, Fuerst HT . Low birth weight and maternal virus diseases. A prospective study of rubella, measles, mumps, chickenpox, and hepatitis. JAMA 1966; 197 (9): 680–684.
Jason E, Eberhart-Phillips MD . Measles in pregnancy: a descriptive study of 58 cases. Obstet Gynecol 1993; 82: 797–801.
Linder N, Tallen-Gopzani E, German B, Duvdevani P, Ferber A, Sirota L . Placental transfer of measles antibodies: effect of gestational age and maternal vaccination status. Vaccine 2004; 22: 1509–1514.
de Muralt G . Maturation of cellular and humoral immunity. In: Stave U. (ed). Perinatal Physiology. Plenum: New York, 1978.
Christensen PE, Schmidt H, Bang HO, Andersen V, Jordal B, Jensen O . An epidemic of measles in southern Greenland, 1951 Measles in virgin soil. The epidemic proper. Acta Med Scand 1953; 144 (6): 450–454.
Koi H, Zhang J, Makrigiannakis A, Getsios S, MacCalman CD, Straus JF III, et al. Syncytiotrophoblast is a barrier to maternal-fetal transmission of herpes simplex virus. Biol Reprod 2005; 67: 1572–1579.
Ohyama M, Fukui T, Tanaka Y, Kato K, Hoshino R, Sugawara T et al. Measles virus infection in the placenta of monozygotic twin. Mod Pathol 2001; 14 (12): 1300–1303.
Bhat P, Anderson DA . Hepatitis B virus translocates across a trophoblastic barrier. J Virol 2007; 81: 7200–7207.
Plumet S, Gelier D . Optimized SYBR green real-timePCR assay to quantify the absolute copy number of measles virus RNAs using gene specific primers. J Virol Methods 2005; 128 (1–2): 79–87.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Go, H., Hashimoto, K., Imamura, T. et al. An extremely low body weight infant born to a mother with measles. J Perinatol 30, 146–148 (2010). https://doi.org/10.1038/jp.2009.111
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/jp.2009.111