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Risk factors for macrosomia in infants born to Latina women

Journal of Perinatology volume 28, pages 743–749 (2008)Cite this article

Abstract

Objective:

To assess risk factors for macrosomic infant birth among Latina women.

Study Design:

Prospective study of Latina women recruited during pregnancy from prenatal clinic at San Francisco General Hospital. Information was obtained through a structured interview and review of medical records.

Result:

A total of 11% of women delivered macrosomic infants (birth weight >4000 g). In unadjusted analyses, significant risk factors for macrosomia included older maternal age, increasing gravidity, previous history of macrosomic birth and pre-pregnancy overweight. After adjusting for confounders using multivariate analyses, older mothers (10-year increments) had an elevated risk of macrosomia (odds ratio (OR) 2.59; 95% confidence interval (CI) 1.28 to 5.24).

Conclusion:

Efforts to reduce macrosomia in Latina women should focus on older mothers.

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Acknowledgements

This study was supported by grants to Dr Fuentes-Afflick from the National Center for Research Resources through a Minority Clinical Associate Physician award (3 M01 RR0083-34S1), a Generalist Physician Faculty Scholar Award from the Robert Wood Johnson Foundation and the National Institutes for Child Health and Human Development (HD 01303). The study interviews were conducted in the General Clinical Research Center at San Francisco General Hospital and were partially supported by grant M01 RR00083-41. Dr Heyman is supported by NIH grant DK 060617.

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Authors and Affiliations

  1. Department of Pediatrics, University of California, San Francisco, CA, USA

    J M Wojcicki, M B Heyman & E Fuentes-Afflick

  2. Department of Clinical Pharmacy, University of California, San Francisco, CA, USA

    N A Hessol

  3. Department of Medicine, University of California, San Francisco, CA, USA

    N A Hessol

  4. Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA

    E Fuentes-Afflick

Authors
  1. J M Wojcicki
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  2. N A Hessol
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  3. M B Heyman
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  4. E Fuentes-Afflick
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Correspondence to E Fuentes-Afflick.

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Wojcicki, J., Hessol, N., Heyman, M. et al. Risk factors for macrosomia in infants born to Latina women. J Perinatol 28, 743–749 (2008). https://doi.org/10.1038/jp.2008.94

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