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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

A pair of twins born after maternal exposure to leflunomide

Journal of Perinatology volume 28, pages 841–842 (2008)Cite this article

Abstract

Leflunomide is a drug used in rheumatoid arthritis with teratogenic and fetotoxic effects. Clinical data on human pregnancies are limited to a few case reports without detailed information whether the mothers did have a washout procedure as suggested by the manufacturer or what type of malformation the offspring showed. We report on a set of twins born after maternal exposure to leflunomide who had a largely normal neonatal outcome, providing information about the washout procedure and the blood level of the active metabolite.

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Acknowledgements

No author received any financial support for this report.

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Authors and Affiliations

  1. Department of Neonatology, University Children's Hospital, Tübingen, Germany

    K Heine & C F Poets

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  1. K Heine
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  2. C F Poets
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Correspondence to C F Poets.

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Heine, K., Poets, C. A pair of twins born after maternal exposure to leflunomide. J Perinatol 28, 841–842 (2008). https://doi.org/10.1038/jp.2008.118

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  • DOI: https://doi.org/10.1038/jp.2008.118

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