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Cardiovascular prevention: relationships between arterial aging and chronic drug treatment

Journal of Human Hypertension volume 25, pages 521–523 (2011)Cite this article

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In hypertension, structural and functional properties of the arterial wall are altered, and morbidity and mortality associated with hypertension are related to the vascular damage affecting several organs.

Going from central to peripheral arteries, the diameter and the composition of the vessel wall vary in important ways. In addition, the aorta and its main branches are highly sensitive to aging and changes in blood pressure while the more distal compartment is the major source of wave reflections and highly sensitive to vasoactive substances.

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Authors and Affiliations

  1. Heart Centre, University Hospital Ghent, Ghent, Belgium

    Tine de Backer

  2. Clinical Pharmacology, University of Ghent, Ghent, Belgium

    Tine de Backer

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  1. Tine de Backer
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Correspondence to Tine de Backer.

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de Backer, T. Cardiovascular prevention: relationships between arterial aging and chronic drug treatment. J Hum Hypertens 25, 521–523 (2011). https://doi.org/10.1038/jhh.2011.30

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