Abstract
Sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) is a central regulator of lipid synthesis and uptake in animal cells. A polymorphic dinucleotide (CA) repeat sequence was isolated from a genomic clone containing the SCAP gene and was mapped to chromosome 3p21.3. High heterozygosity (0.89) makes this polymorphism a useful marker in the genetic study of disorders affecting lipid metabolism.
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Received: March 15, 1999 / Accepted: April 16, 1999
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Nakajima, T., Ota, N., Kodama, T. et al. Isolation and radiation hybrid mapping of a highly polymorphic CA repeat sequence at the SREBP cleavage-activating protein (SCAP) locus. J Hum Genet 44, 350–351 (1999). https://doi.org/10.1007/s100380050175
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DOI: https://doi.org/10.1007/s100380050175