Short Communication | Published:

Cloning, expression analysis, and chromosomal localization of a novel butyrophilin-like receptor

Journal of Human Genetics volume 44, pages 249252 (1999) | Download Citation

Abstract

We isolated a cDNA clone which shows a similarity with human butyrophilin from a human colon mucosa cDNA library. The cDNA is 1964 bases long, with one open reading frame encoding a protein of 433 amino acids. The deduced amino acid sequence shows an overall homology of 36.5% with the human butyrophilin protein. This gene is mainly expressed in small intestine, colon, testis, and leukocytes. The chromosomal location of the gene was determined on the chromosome 5q35 region by polymerase chain reaction-based analysis with both a human/rodent monochromosomal hybrid cell panel and a radiation hybrid mapping panel.

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Affiliations

  1. Department of Virology, the Institute of Medical Science, University of Tokyo, Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan

    • Akiko Shibui
    • , Takeshi Tsunoda
    • , Yutaka Suzuki
    •  & Sumio Sugano
  2. Department of Parasitology, Sinshu University School of Medicine, Matsumoto, Japan

    • Akiko Shibui
    •  & Kazuo Sugane
  3. Genome Research Group, National Institute of Radiological Science, Chiba, Japan

    • Naohiko Seki

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Corresponding author

Correspondence to Sumio Sugano.

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DOI

https://doi.org/10.1007/s100380050153

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