Summary
The transcription factor KBF2 has been characterized as a factor that binds to the NFkB site of mouse major histocompatibility complex (MHC) class I genes and its amino acid sequence has been shown to be identical to those of members of the recombination signalsequence binding protein (RBP-Jk) family. Previous studies by Amakawaet al. (Genomics17, 306–315, 1993) demonstrated that the functional gene is localized at human chromosome 3q25. However, in the present study we showed byin situ hybridization with the functional KBF2/RBPJk cosmid clone that the gene is localized at 9p12-13 and 9q13, namely, at the same loci as pseudogenes that were reported previously (Zhanget al., Jpn J Human Genet39, 391–401, 1994).
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Tang, X., Saito-Ohara, F., Song, J. et al. Assignment of the human gene for KBF2/RBP-Jk to chromosome 9p12-13 and 9q13 by fluorescencein situ hybridization. Jap J Human Genet 42, 337–341 (1997). https://doi.org/10.1007/BF02766956
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DOI: https://doi.org/10.1007/BF02766956