Summary
Coagulation factors VII (F7) and X (F10) were investigated in three patients with terminal deletion of 13q [46,XX,del(13)(q32)], a patient with complete 13 trisomy and a patient with a balanced X;13 translocation [46,X,t(X;13)(p11.21;q12.3)]. Though a patient of terminal 13q- syndrome had normal activities of F7 and F10, the other two patients showed an about 50% deficiency for them. A patient with 13 trisomy and a patient with a X;13 translocation had normal activities of F7 and F10. A 13q- syndrome patient with normal values of coagulation factors VII and X might have an intact terminal portion of chromosome 13, which is not apparent by R-banding.
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Fukushima, Y., Kuroki, Y. & Iizuka, A. Activity and antigen of coagulation factors VII and X in five patients with abnormal chromosome 13. Jap J Human Genet 32, 91–96 (1987). https://doi.org/10.1007/BF01893162
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DOI: https://doi.org/10.1007/BF01893162
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